If your device doesn't even show up in Device Manager (not even as an unknown device), the problem is likely hardware-related. Test your adapter on another computer to confirm if it's functional. A complete lack of detection often points to a dead or damaged USB-to-Serial adapter.
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Here is everything you need to know about why this happens and how to install the correct software to get your device working. Why Version 3.2.0.0 Matters If your device doesn't even show up in
If you’ve ever plugged in a USB-to-Serial adapter only to be met with a yellow warning triangle and the dreaded "This device cannot start (Code 10)" "Phased out" Thus, the search for "Prolific USB to Serial
If you specifically found a file named PL2303_32bit_Setup_v320.exe :
: Newer drivers (e.g., version 3.9.1.0 or later) automatically pushed by Windows Update detect these older or "counterfeit" chips and disable them, showing errors like "Code 10" or the message "PL2303TA DO NOT SUPPORT WINDOWS 11 OR LATER" .